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Lactitol Monhydrate and Ispaghula Husk Granules

This combination is provided by combining a bulkforming laxative in the form of psyllium husk (Ispaghula husk) with an osmotic laxative such as lactitol for Idiopathic constipation and is used to prevent or treat constipation. Constipation is a common problem which can be caused by a number of things. Not eating enough fiber or not drinking enough fluid can cause constipation. Some conditions can cause constipation such as such as pregnancy or lack of exercise or movement (such as being ill in bed) or some medicines. It is a common problem for adults and pediatric patients and can generate considerable suffering for patients due to both the unpleasant physical symptoms and psychological preoccupations that can arise. In this combination, Lactitol is an osmotic disaccharide laxative that increases fecal volume and stimulates peristalsis. Ispaghula husk helps relieve constipation and as a laxative, works by increasing the bulk of stools, which encourages bowels to move the stools through digestive system, which in turn relieves constipation. Bulkforming laxatives absorb water and expand in the colonic lumen; in contrast, osmotic laxatives retain water in the colonic lumen by osmosis. So, both laxatives act to retain water in the colonic lumen thereby counteracting the normal dehydrating action of the colon. By suppressing the dehydration action of the colon, the osmotic laxative produces a fecal stream which is softer, bulkier and easier to expel. These laxatives also help to produce formed stools, without any systemic toxicity.

  • Composition

    Lactitol Monohydrate BP 10 g
    Ispaghula Husk IP 3.5 g

  • Release form

    Husk Granules

  • Category

    Laxative

Indications

Constipation, Fissures, Haemorrhoids, Pregnancy, Pre and postoperative conditions, Mild to moderate hypercholesterolaemia, Prevention of hepatic encephalopathy, Chronic cholecystitis, Acidity, Anorectal disease, Irritable bowel syndrome, and Inflammatory bowel disease or other types of diarrhea.

Pharmacology

Botanically, Isabgol (also called Psyllium & Ispaghula) is Plantago ovata. Sat Ispagol (also called Psyllium Husk & Isaghula Husk) is husk outer membranous covering of the Plantago ovata seeds, which is useful in relieving constipation and has other therapeutic benefits and uses. Ispaghula husk has gentle laxative action that depends on the fiber content, so it is not actually true purgative. It can be categorized under bulk forming laxatives. The flour of Isab gol Husk is added in multigrain flour to enhance nutritive value as well as fiber content of cereal flours. It can absorb 14 times more water than its weight. Therefore, the high amount of liquids or water should be consumed while taking Ispaghula husk. It will also help preventing immediate side effects like choking.

Side Effects

Temporary increase of flatulence and abdominal distension, Rectal irritation, Dangerous potassium loss, Headache, Confusion, Rash, Hypersensitivity reactions.